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c-MYC-Induced AP4 Attenuates DREAM-Mediated Repression by p53

SIMPLE SUMMARY: Deregulated expression of the c-MYC oncogene activates the tumor suppressor p53, which has been suggested to represent a failsafe mechanism against the uncontrolled expansion of tumor cells. Here, we analyzed the role of the c-MYC-induced TFAP4/AP4 gene in this context using a geneti...

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Detalles Bibliográficos
Autores principales: Kaller, Markus, Shi, Wenjing, Hermeking, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954515/
https://www.ncbi.nlm.nih.gov/pubmed/36831504
http://dx.doi.org/10.3390/cancers15041162