Mitochondrial Lipid Peroxidation Is Responsible for Ferroptosis

Ferroptosis induced by erastin (an inhibitor of cystine transport) and butionine sulfoximine (an inhibitor of glutathione biosynthesis) was prevented by the mitochondria-targeted antioxidants SkQ1 and MitoTEMPO. These effects correlate with the prevention of mitochondrial lipid peroxidation, which p...

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Detalles Bibliográficos
Autores principales: Lyamzaev, Konstantin G., Panteleeva, Alisa A., Simonyan, Ruben A., Avetisyan, Armine V., Chernyak, Boris V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954536/
https://www.ncbi.nlm.nih.gov/pubmed/36831278
http://dx.doi.org/10.3390/cells12040611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954536/
https://www.ncbi.nlm.nih.gov/pubmed/36831278
http://dx.doi.org/10.3390/cells12040611

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