Cargando…
miR-34a and IRE1A/XBP-1(S) Form a Double-Negative Feedback Loop to Regulate Hypoxia-Induced EMT, Metastasis, Chemo-Resistance and Autophagy
SIMPLE SUMMARY: The hypoxic tumor microenvironment is a key factor in the formation of metastasis and treatment resistance. We recently identified a new regulatory network consisting of the hypoxia-inducible transcription factor HIF-1A and the p53-inducible miR-34a that determines whether a tumor ce...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954576/ https://www.ncbi.nlm.nih.gov/pubmed/36831485 http://dx.doi.org/10.3390/cancers15041143 |