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Interneuronal In Vivo Transfer of Synaptic Proteins

Neuron-to-neuron transfer of pathogenic α-synuclein species is a mechanism of likely relevance to Parkinson’s disease development. Experimentally, interneuronal α-synuclein spreading from the low brainstem toward higher brain regions can be reproduced by the administration of AAV vectors encoding fo...

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Detalles Bibliográficos
Autores principales: Klinkenberg, Michael, Helwig, Michael, Pinto-Costa, Rita, Rollar, Angela, Rusconi, Raffaella, Di Monte, Donato A., Ulusoy, Ayse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954582/
https://www.ncbi.nlm.nih.gov/pubmed/36831238
http://dx.doi.org/10.3390/cells12040569