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P21 Overexpression Promotes Cell Death and Induces Senescence in Human Glioblastoma

SIMPLE SUMMARY: Current standard care for high-grade glioma involves maximal safe resection followed by chemoradiation. Recent studies showed that surviving cancer cells with an initially senescent phenotype following chemoradiation could escape senescence over time, giving rise to tumor cells that...

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Detalles Bibliográficos
Autores principales: Mansour, Moustafa A., Rahman, Masum, Ayad, Ahmad A., Warrington, Arthur E., Burns, Terry C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954583/
https://www.ncbi.nlm.nih.gov/pubmed/36831620
http://dx.doi.org/10.3390/cancers15041279