A New Optimized Version of a Colorectal Cancer-Targeted Immunotoxin Based on a Non-Immunogenic Variant of the Ribotoxin α-Sarcin

SIMPLE SUMMARY: Antitumor therapy with immunotoxins is limited by problems of immunogenicity and low efficacy in solid tumors. The different strategies to solve these problems include obtaining non-immunogenic variants of the toxins used as well as optimizing their release into the cytosol to increa...

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Detalles Bibliográficos
Autores principales: Narbona, Javier, Gordo, Rubén G., Tomé-Amat, Jaime, Lacadena, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954630/
https://www.ncbi.nlm.nih.gov/pubmed/36831456
http://dx.doi.org/10.3390/cancers15041114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954630/
https://www.ncbi.nlm.nih.gov/pubmed/36831456
http://dx.doi.org/10.3390/cancers15041114

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