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A New Optimized Version of a Colorectal Cancer-Targeted Immunotoxin Based on a Non-Immunogenic Variant of the Ribotoxin α-Sarcin
SIMPLE SUMMARY: Antitumor therapy with immunotoxins is limited by problems of immunogenicity and low efficacy in solid tumors. The different strategies to solve these problems include obtaining non-immunogenic variants of the toxins used as well as optimizing their release into the cytosol to increa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954630/ https://www.ncbi.nlm.nih.gov/pubmed/36831456 http://dx.doi.org/10.3390/cancers15041114 |