Cargando…

Complementary Cell Lines for Protease Gene-Deleted Single-Cycle Adenovirus Vectors

To increase the safety of adenovirus vector (AdV)-based therapy without reducing its efficacy, a single-cycle adenovirus vector (SC-AdV) with a deletion in the protease gene (PS) was developed in order to be used as a substitute for the replication-competent adenovirus (RC-AdV). Since no infectious...

Descripción completa

Detalles Bibliográficos
Autores principales: Elahi, Seyyed Mehdy, Nazemi-Moghaddam, Nazila, Guilbault, Claire, Simoneau, Mélanie, Gilbert, Rénald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954690/
https://www.ncbi.nlm.nih.gov/pubmed/36831286
http://dx.doi.org/10.3390/cells12040619