Combined Inhibition of IAPs and WEE1 Enhances TNFα- and Radiation-Induced Cell Death in Head and Neck Squamous Carcinoma

SIMPLE SUMMARY: Both IAP and WEE1 inhibitors have demonstrated therapeutic efficacy in in vitro pre-clinical models of head and neck squamous cell carcinoma (HNSCC). Here, we demonstrate that dual treatment with IAP and WEE1 inhibitors sensitizes both HPV-negative and HPV-positive HNSCC cells to bot...

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Detalles Bibliográficos
Autores principales: Toni, Tiffany, Viswanathan, Ramya, Robbins, Yvette, Gunti, Sreenivasulu, Yang, Xinping, Huynh, Angel, Cheng, Hui, Sowers, Anastasia L., Mitchell, James B., Allen, Clint T., Morgan, Ethan L., Van Waes, Carter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954698/
https://www.ncbi.nlm.nih.gov/pubmed/36831373
http://dx.doi.org/10.3390/cancers15041029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954698/
https://www.ncbi.nlm.nih.gov/pubmed/36831373
http://dx.doi.org/10.3390/cancers15041029

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