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CD169(+) Macrophages in Primary Breast Tumors Associate with Tertiary Lymphoid Structures, T(regs) and a Worse Prognosis for Patients with Advanced Breast Cancer

SIMPLE SUMMARY: We here show that CD169(+) TAMs in primary breast tumors are associated with tertiary lymphoid-like structures (TLLSs), T(reg) and B(reg) signatures, and a worse prognosis for the patient. In contrast, CD169(+) TAMs and TLLSs present in lymph node metastases were associated with bett...

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Detalles Bibliográficos
Autores principales: Briem, Oscar, Källberg, Eva, Kimbung, Siker, Veerla, Srinivas, Stenström, Jenny, Hatschek, Thomas, Hagerling, Catharina, Hedenfalk, Ingrid, Leandersson, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954705/
https://www.ncbi.nlm.nih.gov/pubmed/36831605
http://dx.doi.org/10.3390/cancers15041262