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Does the Gain of Total Neoadjuvant Therapy Outweigh the Harm in Rectal Cancer? Importance of the ATRESS (neoAdjuvant Therapy-RElated Shortening of Survival) Phenomenon: A Systematic Review
SIMPLE SUMMARY: Total neoadjuvant therapy (TNT) refers to delivering both (chemo)radiation and chemotherapy before surgery, aiming to reduce incidence of distant metastases. Indeed, in two randomised trials, TNT reduced distant metastases incidence compared with neoadjuvant chemoradiation, but witho...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954766/ https://www.ncbi.nlm.nih.gov/pubmed/36831360 http://dx.doi.org/10.3390/cancers15041016 |