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Does the Gain of Total Neoadjuvant Therapy Outweigh the Harm in Rectal Cancer? Importance of the ATRESS (neoAdjuvant Therapy-RElated Shortening of Survival) Phenomenon: A Systematic Review

SIMPLE SUMMARY: Total neoadjuvant therapy (TNT) refers to delivering both (chemo)radiation and chemotherapy before surgery, aiming to reduce incidence of distant metastases. Indeed, in two randomised trials, TNT reduced distant metastases incidence compared with neoadjuvant chemoradiation, but witho...

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Detalles Bibliográficos
Autores principales:	Socha, Joanna, Bujko, Krzysztof
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Systematic Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954766/ https://www.ncbi.nlm.nih.gov/pubmed/36831360 http://dx.doi.org/10.3390/cancers15041016

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