Cargando…

Role of C-Terminal Phosphorylation of Lamin A in DNA Damage and Cellular Senescence

The nuclear matrix protein lamin A is a multifunctional protein with roles in DNA replication and repair, gene activation, transcriptional regulation, and maintenance of higher-order chromatin structure. Phosphorylation is the main determinant of lamin A mobility in the nucleus and nuclear membrane...

Descripción completa

Detalles Bibliográficos
Autores principales: Ao, Ying, Wu, Zhuping, Liao, Zhiwei, Lan, Juncong, Zhang, Jie, Sun, Pengfei, Liu, Baohua, Wang, Zimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954792/
https://www.ncbi.nlm.nih.gov/pubmed/36831305
http://dx.doi.org/10.3390/cells12040639