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Role of C-Terminal Phosphorylation of Lamin A in DNA Damage and Cellular Senescence
The nuclear matrix protein lamin A is a multifunctional protein with roles in DNA replication and repair, gene activation, transcriptional regulation, and maintenance of higher-order chromatin structure. Phosphorylation is the main determinant of lamin A mobility in the nucleus and nuclear membrane...
Autores principales: | Ao, Ying, Wu, Zhuping, Liao, Zhiwei, Lan, Juncong, Zhang, Jie, Sun, Pengfei, Liu, Baohua, Wang, Zimei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9954792/ https://www.ncbi.nlm.nih.gov/pubmed/36831305 http://dx.doi.org/10.3390/cells12040639 |
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