Synthesis, Molecular Docking, and Dynamic Simulation Targeting Main Protease (Mpro) of New, Thiazole Clubbed Pyridine Scaffolds as Potential COVID-19 Inhibitors

Many biological activities of pyridine and thiazole derivatives have been reported, including antiviral activity and, more recently, as COVID-19 inhibitors. Thus, in this paper, we designed, synthesized, and characterized a novel series of N-aminothiazole-hydrazineethyl-pyridines, beginning with a N...

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Detalles Bibliográficos
Autores principales: Alghamdi, Adel, Abouzied, Amr S., Alamri, Abdulwahab, Anwar, Sirajudheen, Ansari, Mukhtar, Khadra, Ibrahim, Zaki, Yasser H., Gomha, Sobhi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955078/
https://www.ncbi.nlm.nih.gov/pubmed/36826038
http://dx.doi.org/10.3390/cimb45020093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955078/
https://www.ncbi.nlm.nih.gov/pubmed/36826038
http://dx.doi.org/10.3390/cimb45020093

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