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Analysis of the Passage Times for Unfolding/Folding of the Adenine Riboswitch Aptamer
[Image: see text] The conformational transitions of the adenosine deaminase A-riboswitch aptamer both with and without ligand binding are investigated within the tenets of the generalized Langevin equation in a complex viscoelastic cellular environment. Steered molecular dynamics (SMD) simulations a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955275/ https://www.ncbi.nlm.nih.gov/pubmed/36855421 http://dx.doi.org/10.1021/acsphyschemau.1c00056 |