Tumor Suppressor p53 Down-Regulates Programmed Cell Death Protein 4 (PDCD4) Expression

The programmed cell death protein 4 (PDCD4), a well-known tumor suppressor, inhibits translation initiation and cap-dependent translation by inhibiting the helicase activity of EIF4A. The EIF4A tends to target mRNAs with a structured 5′-UTR. In addition, PDCD4 can also prevent tumorigenesis by inhib...

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Detalles Bibliográficos
Autores principales: Yang, William H., George, Andrew P., Wang, Chiung-Min, Yang, Richard H., Duncan, Avery M., Patel, Darshti, Neil, Zachery D., Yang, Wei-Hsiung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955764/
https://www.ncbi.nlm.nih.gov/pubmed/36826085
http://dx.doi.org/10.3390/curroncol30020124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955764/
https://www.ncbi.nlm.nih.gov/pubmed/36826085
http://dx.doi.org/10.3390/curroncol30020124

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