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Case Report: Rare IKZF1 Gene Fusions Identified in Neonate with Congenital KMT2A-Rearranged Acute Lymphoblastic Leukemia

Chromosomal rearrangements involving the KMT2A gene occur frequently in acute lymphoblastic leukaemia (ALL). KMT2A-rearranged ALL (KMT2Ar ALL) has poor long-term survival rates and is the most common ALL subtype in infants less than 1 year of age. KMT2Ar ALL frequently occurs with additional chromos...

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Detalles Bibliográficos
Autores principales: Eadie, Laura N., Rehn, Jacqueline A., Breen, James, Osborn, Michael P., Jessop, Sophie, Downes, Charlotte E. J., Heatley, Susan L., McClure, Barbara J., Yeung, David T., Revesz, Tamas, Saxon, Benjamin, White, Deborah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956107/
https://www.ncbi.nlm.nih.gov/pubmed/36833191
http://dx.doi.org/10.3390/genes14020264