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Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis

Thermogenesis by uncoupling protein 1 (UCP1) is one of the primary mechanisms by which brown adipose tissue (BAT) increases energy expenditure. UCP1 resides in the inner mitochondrial membrane (IMM), where it dissipates membrane potential independent of adenosine triphosphate (ATP) synthase. Here, w...

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Detalles Bibliográficos
Autores principales: Johnson, Jordan M., Peterlin, Alek D., Balderas, Enrique, Sustarsic, Elahu G., Maschek, J. Alan, Lang, Marisa J., Jara-Ramos, Alejandro, Panic, Vanja, Morgan, Jeffrey T., Villanueva, Claudio J., Sanchez, Alejandro, Rutter, Jared, Lodhi, Irfan J., Cox, James E., Fisher-Wellman, Kelsey H., Chaudhuri, Dipayan, Gerhart-Hines, Zachary, Funai, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956115/
https://www.ncbi.nlm.nih.gov/pubmed/36827367
http://dx.doi.org/10.1126/sciadv.ade7864