Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes

Immunological chaperones tapasin and TAP binding protein, related (TAPBPR) play key roles in antigenic peptide optimization and quality control of nascent class I major histocompatibility complex (MHC-I) molecules. The polymorphic nature of MHC-I proteins leads to a range of allelic dependencies on...

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Detalles Bibliográficos
Autores principales: Sun, Yi, Papadaki, Georgia F., Devlin, Christine A., Danon, Julia N., Young, Michael C., Winters, Trenton J., Burslem, George M., Procko, Erik, Sgourakis, Nikolaos G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956121/
https://www.ncbi.nlm.nih.gov/pubmed/36827371
http://dx.doi.org/10.1126/sciadv.ade7151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956121/
https://www.ncbi.nlm.nih.gov/pubmed/36827371
http://dx.doi.org/10.1126/sciadv.ade7151

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