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Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes

Immunological chaperones tapasin and TAP binding protein, related (TAPBPR) play key roles in antigenic peptide optimization and quality control of nascent class I major histocompatibility complex (MHC-I) molecules. The polymorphic nature of MHC-I proteins leads to a range of allelic dependencies on...

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Detalles Bibliográficos
Autores principales:	Sun, Yi, Papadaki, Georgia F., Devlin, Christine A., Danon, Julia N., Young, Michael C., Winters, Trenton J., Burslem, George M., Procko, Erik, Sgourakis, Nikolaos G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956121/ https://www.ncbi.nlm.nih.gov/pubmed/36827371 http://dx.doi.org/10.1126/sciadv.ade7151

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