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Genetic Interaction of tRNA-Dependent Mistranslation with Fused in Sarcoma Protein Aggregates

High-fidelity protein synthesis requires properly aminoacylated transfer RNAs (tRNAs), yet diverse cell types, from bacteria to humans, show a surprising ability to tolerate errors in translation resulting from mutations in tRNAs, aminoacyl-tRNA synthetases, and other components of protein synthesis...

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Detalles Bibliográficos
Autores principales: Lant, Jeremy T., Hasan, Farah, Briggs, Julia, Heinemann, Ilka U., O’Donoghue, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956149/
https://www.ncbi.nlm.nih.gov/pubmed/36833445
http://dx.doi.org/10.3390/genes14020518