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Genetic Interaction of tRNA-Dependent Mistranslation with Fused in Sarcoma Protein Aggregates
High-fidelity protein synthesis requires properly aminoacylated transfer RNAs (tRNAs), yet diverse cell types, from bacteria to humans, show a surprising ability to tolerate errors in translation resulting from mutations in tRNAs, aminoacyl-tRNA synthetases, and other components of protein synthesis...
Autores principales: | Lant, Jeremy T., Hasan, Farah, Briggs, Julia, Heinemann, Ilka U., O’Donoghue, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956149/ https://www.ncbi.nlm.nih.gov/pubmed/36833445 http://dx.doi.org/10.3390/genes14020518 |
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