Intranasal Administration of Dolutegravir-Loaded Nanoemulsion-Based In Situ Gel for Enhanced Bioavailability and Direct Brain Targeting

Dolutegravir’s therapeutic effectiveness in the management of neuroAIDS is mainly limited by its failure to cross the blood–brain barrier. However, lipid-based nanovesicles such as nanoemulsions have demonstrated their potential for the brain targeting of various drugs by intranasal delivery. Thus,...

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Detalles Bibliográficos
Autores principales: Nair, Anroop B., Chaudhary, Sunita, Jacob, Shery, Patel, Dhwani, Shinu, Pottathil, Shah, Hiral, Chaudhary, Ankit, Aldhubiab, Bandar, Almuqbil, Rashed M., Alnaim, Ahmed S., Alqattan, Fatemah, Shah, Jigar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956165/
https://www.ncbi.nlm.nih.gov/pubmed/36826300
http://dx.doi.org/10.3390/gels9020130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956165/
https://www.ncbi.nlm.nih.gov/pubmed/36826300
http://dx.doi.org/10.3390/gels9020130

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