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A Chemoptogenetic Tool for Spatiotemporal Induction of Oxidative DNA Lesions In Vivo

Oxidative nuclear DNA damage increases in all tissues with age in multiple animal models, as well as in humans. However, the increase in DNA oxidation varies from tissue to tissue, suggesting that certain cells/tissues may be more vulnerable to DNA damage than others. The lack of a tool that can con...

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Detalles Bibliográficos
Autores principales: Han, Suhao, Sims, Austin, Aceto, Anthony, Schmidt, Brigitte F., Bruchez, Marcel P., Gurkar, Aditi U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956269/
https://www.ncbi.nlm.nih.gov/pubmed/36833412
http://dx.doi.org/10.3390/genes14020485