Towards a Cure for HARS Disease

Histidyl-tRNA synthetase (HARS) ligates histidine to its cognate transfer RNA (tRNA(His)). Mutations in HARS cause the human genetic disorders Usher syndrome type 3B (USH3B) and Charcot-Marie-Tooth syndrome type 2W (CMT2W). Treatment for these diseases remains symptomatic, and no disease specific tr...

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Detalles Bibliográficos
Autores principales: Wilhelm, Sarah D. P., Kenana, Rosan, Qiu, Yi, O’Donoghue, Patrick, Heinemann, Ilka U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956352/
https://www.ncbi.nlm.nih.gov/pubmed/36833180
http://dx.doi.org/10.3390/genes14020254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956352/
https://www.ncbi.nlm.nih.gov/pubmed/36833180
http://dx.doi.org/10.3390/genes14020254

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