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Pharmacogenetic allele variant frequencies: An analysis of the VA’s Million Veteran Program (MVP) as a representation of the diversity in US population

We present allele frequencies of pharmacogenomics relevant variants across multiple ancestry in a sample representative of the US population. We analyzed 658,582 individuals with genotype data and extracted pharmacogenomics relevant single nucleotide variant (SNV) alleles, human leukocyte antigens (...

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Detalles Bibliográficos
Autores principales: Markianos, Kyriacos, Dong, Frederic, Gorman, Bryan, Shi, Yunling, Dochtermann, Daniel, Saxena, Uma, Devineni, Poornima, Moser, Jennifer, Muralidhar, Sumitra, Ramoni, Rachel, Tsao, Philip, Pyarajan, Saiju, Przygodzki, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956596/
https://www.ncbi.nlm.nih.gov/pubmed/36827430
http://dx.doi.org/10.1371/journal.pone.0274339