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Transcellular chaperone signaling is an intercellular stress-response distinct from the HSF-1–mediated heat shock response

Organismal proteostasis is maintained by intercellular signaling processes including cell nonautonomous stress responses such as transcellular chaperone signaling (TCS). When TCS is activated upon tissue-specific knockdown of hsp-90 in the Caenorhabditis elegans intestine, heat-inducible hsp-70 is i...

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Detalles Bibliográficos
Autores principales: Miles, Jay, Townend, Sarah, Milonaitytė, Dovilė, Smith, William, Hodge, Francesca, Westhead, David R., van Oosten-Hawle, Patricija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956597/
https://www.ncbi.nlm.nih.gov/pubmed/36780563
http://dx.doi.org/10.1371/journal.pbio.3001605