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Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome
During infection of mammalian hosts, African trypanosomes thwart immunity using antigenic variation of the dense Variant Surface Glycoprotein (VSG) coat, accessing a large repertoire of several thousand genes and pseudogenes, and switching to antigenically distinct copies. The parasite is transferre...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956791/ https://www.ncbi.nlm.nih.gov/pubmed/36780870 http://dx.doi.org/10.1371/journal.pntd.0011093 |