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Copy number footprints of platinum-based anticancer therapies

Recently, distinct mutational footprints observed in metastatic tumors, secondary malignancies and normal human tissues have been demonstrated to be caused by the exposure to several chemotherapeutic drugs. These characteristic mutations originate from specific lesions caused by these chemicals to t...

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Detalles Bibliográficos
Autores principales: Gonzalez, Santiago, Lopez-Bigas, Nuria, Gonzalez-Perez, Abel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956877/
https://www.ncbi.nlm.nih.gov/pubmed/36780550
http://dx.doi.org/10.1371/journal.pgen.1010634