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Copy number footprints of platinum-based anticancer therapies
Recently, distinct mutational footprints observed in metastatic tumors, secondary malignancies and normal human tissues have been demonstrated to be caused by the exposure to several chemotherapeutic drugs. These characteristic mutations originate from specific lesions caused by these chemicals to t...
Autores principales: | Gonzalez, Santiago, Lopez-Bigas, Nuria, Gonzalez-Perez, Abel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956877/ https://www.ncbi.nlm.nih.gov/pubmed/36780550 http://dx.doi.org/10.1371/journal.pgen.1010634 |
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