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Sex-Specific Effects of the Genetic Variant rs10487505 Upstream of leptin in the Development of Obesity

The SNP rs10487505 in the promotor region of the leptin gene was reported to be associated with decreased circulating leptin and increased body mass index (BMI). However, the phenotypic outcomes affected by rs10487505 in the leptin regulatory pathway have not been systematically studied. Therefore,...

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Detalles Bibliográficos
Autores principales: Molder, Janine, Guiu-Jurado, Esther, Moulla, Yusef, Stroh, Christine, Dietrich, Arne, Schön, Michael R., Gärtner, Daniel, Lohmann, Tobias, Dressler, Miriam, Stumvoll, Michael, Kovacs, Peter, Blüher, Matthias, Klöting, Nora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956914/
https://www.ncbi.nlm.nih.gov/pubmed/36833305
http://dx.doi.org/10.3390/genes14020378