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Understanding Drug Resistance of Wild-Type and L38HL Insertion Mutant of HIV-1 C Protease to Saquinavir

Acquired immunodeficiency syndrome (AIDS) is one of the most challenging infectious diseases to treat on a global scale. Understanding the mechanisms underlying the development of drug resistance is necessary for novel therapeutics. HIV subtype C is known to harbor mutations at critical positions of...

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Detalles Bibliográficos
Autores principales: Venkatachalam, Sankaran, Murlidharan, Nisha, Krishnan, Sowmya R., Ramakrishnan, C., Setshedi, Mpho, Pandian, Ramesh, Barh, Debmalya, Tiwari, Sandeep, Azevedo, Vasco, Sayed, Yasien, Gromiha, M. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957153/
https://www.ncbi.nlm.nih.gov/pubmed/36833460
http://dx.doi.org/10.3390/genes14020533