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New Insights into the Inhibition of Hesperetin on Polyphenol Oxidase: Inhibitory Kinetics, Binding Characteristics, Conformational Change and Computational Simulation

The inhibitory activity of hesperetin on polyphenol oxidase (PPO) and their interaction characteristics were investigated using multiple spectroscopic methods and computational simulation. Hesperetin, a mixed inhibitor, reversibly inhibited PPO activity, and its half-maximum inhibitory concentration...

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Detalles Bibliográficos
Autores principales: Hong, Xinyue, Luo, Xiaoqiao, Wang, Langhong, Gong, Deming, Zhang, Guowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957399/
https://www.ncbi.nlm.nih.gov/pubmed/36832979
http://dx.doi.org/10.3390/foods12040905