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W-Compound can be used as a Biomarker for Fetal Thyroid Function and a Potential Tool for Screening Congenital Hypothyroidism

Sulfoconjugation is the major pathway for thyroid hormone (TH) metabolism, converting T4 to inactive metabolites, T4S, rT3S, and T3S in fetus, via sulfotransferases (SULT) and type 3 deiodinase in gestation. Consistent with high production rate of T4S and rT3S, there are high serum sulfated iodothyr...

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Detalles Bibliográficos
Autores principales: Wu, Sing-Yung, Zhao, Haibo, Xi, Bi-Xin, Chen, Dong-Bao, Fucito, Maria E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957539/
https://www.ncbi.nlm.nih.gov/pubmed/36843622