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Single-molecule imaging reveals translation-dependent destabilization of mRNAs

The relationship between mRNA translation and decay is incompletely understood, with conflicting reports suggesting that translation can either promote decay or stabilize mRNAs. The effect of translation on mRNA decay has mainly been studied using ensemble measurements and global transcription and t...

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Detalles Bibliográficos
Autores principales: Dave, Pratik, Roth, Gregory, Griesbach, Esther, Mateju, Daniel, Hochstoeger, Tobias, Chao, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957601/
https://www.ncbi.nlm.nih.gov/pubmed/36731471
http://dx.doi.org/10.1016/j.molcel.2023.01.013