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hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts

BACKGROUND: Intestinal fibrosis, one of the complications of inflammatory bowel disease (IBD), is associated with fistula and intestinal stricture formation. There are currently no treatments for fibrosis. Mesenchymal stem cell-derived exosomes have been proven to exert inhibitory and reversal effec...

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Detalles Bibliográficos
Autores principales: Wang, Yifei, Zhang, Yaqin, Lu, Bing, Xi, Jianbo, Ocansey, Dickson Kofi Wiredu, Mao, Fei, Hao, Donglin, Yan, Yongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957621/
https://www.ncbi.nlm.nih.gov/pubmed/36845967
http://dx.doi.org/10.1155/2023/2828981