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Curcumin Ameliorates Age-Induced Tight Junction Impaired in Porcine Sertoli Cells by Inactivating the NLRP3 Inflammasome through the AMPK/SIRT3/SOD2/mtROS Signaling Pathway

Blood-testis barrier (BTB) made of concomitant junction apparatus between Sertoli cells (SCs) is crucial for spermatogenesis. The tight junction (TJ) function is impaired in SCs with age, exhibiting an intimate relationship to testicular dysfunction induced by age. In this study, compared with those...

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Detalles Bibliográficos
Autores principales: Xiao, Longfei, Fang, Zihao, Wang, Qian, Sheng, Xihui, Qi, Xiaolong, Xing, Kai, Guo, Yong, Ni, Hemin, Wang, Xiangguo, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957632/
https://www.ncbi.nlm.nih.gov/pubmed/36846717
http://dx.doi.org/10.1155/2023/1708251