Structural modelling of human complement FHR1 and two of its synthetic derivatives provides insight into their in-vivo functions

Human complement is the first line of defence against invading pathogens and is involved in tissue homeostasis. Complement-targeted therapies to treat several diseases caused by a dysregulated complement are highly desirable. Despite huge efforts invested in their development, only very few are curr...

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Detalles Bibliográficos
Autores principales: Ruiz-Molina, Natalia, Parsons, Juliana, Decker, Eva L., Reski, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957715/
https://www.ncbi.nlm.nih.gov/pubmed/36851916
http://dx.doi.org/10.1016/j.csbj.2023.02.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957715/
https://www.ncbi.nlm.nih.gov/pubmed/36851916
http://dx.doi.org/10.1016/j.csbj.2023.02.002

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