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Structural modelling of human complement FHR1 and two of its synthetic derivatives provides insight into their in-vivo functions
Human complement is the first line of defence against invading pathogens and is involved in tissue homeostasis. Complement-targeted therapies to treat several diseases caused by a dysregulated complement are highly desirable. Despite huge efforts invested in their development, only very few are curr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957715/ https://www.ncbi.nlm.nih.gov/pubmed/36851916 http://dx.doi.org/10.1016/j.csbj.2023.02.002 |