Spatiotemporal view of malignant histogenesis and macroevolution via formation of polyploid giant cancer cells

To understand how malignant tumors develop, we tracked cell membrane, nuclear membrane, spindle, and cell cycle dynamics in polyploid giant cancer cells (PGCCs) during the formation of high-grade serous carcinoma organoids using long-term time-lapse imaging. Single cells underwent traditional mitosi...

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Detalles Bibliográficos
Autores principales: Li, Xiaoran, Zhong, Yanping, Zhang, Xudong, Sood, Anil K., Liu, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957731/
https://www.ncbi.nlm.nih.gov/pubmed/36596845
http://dx.doi.org/10.1038/s41388-022-02588-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957731/
https://www.ncbi.nlm.nih.gov/pubmed/36596845
http://dx.doi.org/10.1038/s41388-022-02588-0

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