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Spatiotemporal view of malignant histogenesis and macroevolution via formation of polyploid giant cancer cells
To understand how malignant tumors develop, we tracked cell membrane, nuclear membrane, spindle, and cell cycle dynamics in polyploid giant cancer cells (PGCCs) during the formation of high-grade serous carcinoma organoids using long-term time-lapse imaging. Single cells underwent traditional mitosi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957731/ https://www.ncbi.nlm.nih.gov/pubmed/36596845 http://dx.doi.org/10.1038/s41388-022-02588-0 |