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Emergent dynamics of underlying regulatory network links EMT and androgen receptor-dependent resistance in prostate cancer

Advanced prostate cancer patients initially respond to hormone therapy, be it in the form of androgen deprivation therapy or second-generation hormone therapies, such as abiraterone acetate or enzalutamide. However, most men with prostate cancer eventually develop hormone therapy resistance. This re...

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Detalles Bibliográficos
Autores principales: Jindal, Rashi, Nanda, Abheepsa, Pillai, Maalavika, Ware, Kathryn E., Singh, Divyoj, Sehgal, Manas, Armstrong, Andrew J., Somarelli, Jason A., Jolly, Mohit Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957767/
https://www.ncbi.nlm.nih.gov/pubmed/36851919
http://dx.doi.org/10.1016/j.csbj.2023.01.031