Mass spectrometry imaging–based assays for aminotransferase activity reveal a broad substrate spectrum for a previously uncharacterized enzyme

Aminotransferases (ATs) catalyze pyridoxal 5′-phosphate–dependent transamination reactions between amino donor and keto acceptor substrates and play central roles in nitrogen metabolism of all organisms. ATs are involved in the biosynthesis and degradation of both proteinogenic and nonproteinogenic...

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Detalles Bibliográficos
Autores principales: de Raad, Markus, Koper, Kaan, Deng, Kai, Bowen, Benjamin P., Maeda, Hiroshi A., Northen, Trent R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957770/
https://www.ncbi.nlm.nih.gov/pubmed/36702250
http://dx.doi.org/10.1016/j.jbc.2023.102939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957770/
https://www.ncbi.nlm.nih.gov/pubmed/36702250
http://dx.doi.org/10.1016/j.jbc.2023.102939

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