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Obstructing Salmonella typhi's virulence in eukaryotic cells through design of its SipB protein antagonists

OBJECTIVE: Typhoid fever, a disease caused by Salmonella typhi, is a leading cause of morbidity and mortality, particularly in developing nations. The evolution of resistance mechanisms to existing antibiotics has necessitated a search for newer drug candidates. This study used computer aided drug d...

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Detalles Bibliográficos
Autores principales: Ameji, John P., Uzairu, Adamu, Shallangwa, Gideon A., Uba, Sani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taibah University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957885/
https://www.ncbi.nlm.nih.gov/pubmed/36852248
http://dx.doi.org/10.1016/j.jtumed.2022.12.010