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Enhanced mitochondrial biogenesis promotes neuroprotection in human pluripotent stem cell derived retinal ganglion cells

Mitochondrial dysfunctions are widely afflicted in central nervous system (CNS) disorders with minimal understanding on how to improve mitochondrial homeostasis to promote neuroprotection. Here we have used human stem cell differentiated retinal ganglion cells (hRGCs) of the CNS, which are highly se...

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Detalles Bibliográficos
Autores principales: Surma, Michelle, Anbarasu, Kavitha, Dutta, Sayanta, Olivera Perez, Leonardo J., Huang, Kang-Chieh, Meyer, Jason S., Das, Arupratan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957998/
https://www.ncbi.nlm.nih.gov/pubmed/36828933
http://dx.doi.org/10.1038/s42003-023-04576-w