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Selective emergence of antibody-secreting cells in the multiple sclerosis brain

BACKGROUND: Although distinct brain-homing B cells have been identified in multiple sclerosis (MS), it is unknown how these further evolve to contribute to local pathology. We explored B-cell maturation in the central nervous system (CNS) of MS patients and determined their association with immunogl...

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Detalles Bibliográficos
Autores principales: Bogers, Laurens, Engelenburg, Hendrik J., Janssen, Malou, Unger, Peter-Paul A., Melief, Marie-José, Wierenga-Wolf, Annet F., Hsiao, Cheng-Chih, Mason, Matthew R.J., Hamann, Jörg, van Langelaar, Jamie, Smolders, Joost, van Luijn, Marvin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958261/
https://www.ncbi.nlm.nih.gov/pubmed/36796230
http://dx.doi.org/10.1016/j.ebiom.2023.104465