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Endocannabinoids enhance hK(V)7.1/KCNE1 channel function and shorten the cardiac action potential and QT interval

BACKGROUND: Genotype-positive patients who suffer from the cardiac channelopathy Long QT Syndrome (LQTS) may display a spectrum of clinical phenotypes, with often unknown causes. Therefore, there is a need to identify factors influencing disease severity to move towards an individualized clinical ma...

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Detalles Bibliográficos
Autores principales: Hiniesto-Iñigo, Irene, Castro-Gonzalez, Laura M., Corradi, Valentina, Skarsfeldt, Mark A., Yazdi, Samira, Lundholm, Siri, Nikesjö, Johan, Noskov, Sergei Yu, Bentzen, Bo Hjorth, Tieleman, D. Peter, Liin, Sara I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958262/
https://www.ncbi.nlm.nih.gov/pubmed/36796231
http://dx.doi.org/10.1016/j.ebiom.2023.104459