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Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV-infected intrahepatic cholangiocarcinoma

Despite the epidemiological association between intrahepatic cholangiocarcinoma (ICC) and hepatitis B virus (HBV) infection, little is known about the relevant oncogenic effects. A cohort of 32 HBV-infected ICC and 89 non-HBV-ICC patients were characterized using whole-exome sequencing, proteomic an...

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Detalles Bibliográficos
Autores principales: Shen, Yifei, Xu, Shuaishuai, Ye, Chanqi, Li, Qiong, Chen, Ruyin, Wu, Wei, Jiang, Qi, Jia, Yunlu, Zhang, Xiaochen, Fan, Longjiang, Fu, Wenguang, Jiang, Ming, Chen, Jinzhang, Timko, Michael P., Zhao, Peng, Ruan, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958296/
https://www.ncbi.nlm.nih.gov/pubmed/36852159
http://dx.doi.org/10.1016/j.isci.2023.106003