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Protein kinase A activation alleviates cataract formation via increased gap junction intercellular communication

Cataract is the leading cause of blindness worldwide. Here, we reported a potential, effective therapeutic mean for cataract prevention and treatment. Gap junction communication, an important mechanism in maintaining lens transparency, is increased by protein kinase A (PKA). We found that PKA activa...

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Detalles Bibliográficos
Autores principales: Du, Yu, Tong, Yuxin, Quan, Yumeng, Wang, Guangyan, Cheng, Hongyun, Gu, Sumin, Jiang, Jean X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958365/
https://www.ncbi.nlm.nih.gov/pubmed/36852280
http://dx.doi.org/10.1016/j.isci.2023.106114